What Are the Chances My Children Will Inherit Ulcerative Colitis or Crohn's Disease?

Updated on March 21, 2018
angela_michelle profile image

At 17, Angela was diagnosed with ulcerative colitis. At 20, her colon was removed. She has a passion to share her knowledge of the disease.

Source

Is Ulcerative Colitis and Crohn's Hereditary?

Ulcerative colitis and Crohn's, both of which are inflammatory bowel diseases (IBD), can be hereditary diseases. A child who has a sibling or parent with an IBD has a twenty percent chance of being diagnosed with one of these in their lifetime. At this time, it is impossible to genetically test who is going to get the disease or who will not; they have not yet identified a gene that causes IBDs.

Crohn's and ulcerative colitis are unique in that they are so interrelated that if a parent or sibling has one, another relative is just as likely to have the other one. This means that if ulcerative colitis runs in your family, a person is just as likely to have Crohn's as ulcerative colitis.

Just as with any other disease, the odds increase if both parents are diagnosed. The likelihood drastically increases up to an eighty percent chance of having one or the other if both parents have an IBD. The severity of the illness, on the other hand, is not hereditary. One person may have a mild case that is easily managed through diet and medication, while another person cannot get theirs under control no matter what they try and eventually will need surgery in order to place it in remission.

If you were diagnosed with an IBD, what age were you when you were diagnosed?

See results

At What Age Do People Tend to Get Diagnosed?

Unfortunately, just as you cannot predict how severe a child's disease will be, you may not be able to tell whether they have it until they are adults.

Crohn's is common to appear in all age groups equally, although most people are diagnosed before thirty-years old. Ulcerative colitis, on the other hand, has a high tendency to show up at two different times in one's life. Most people have their first symptoms in their teens or twenties. The likelihood increases again when the person is fifty to sixty-five. This is believed to be due to the shift in hormones that occurs at both of these ages. Yet, any person of any age can be diagnosed and/or show symptoms of ulcerative colitis.

Source

What Races Are Most Likely to Have an IBD?

Since the disease is genetic, some races are more apt to be diagnosed with an inflammatory bowel disease than others. Asian or African descendants are unlikely to have either of these diseases, while Caucasians have the highest tendency. Also those who have Jewish ancestry have a higher likelihood than non-Jewish ancestry to have an IBD. Still, any person of any race may be diagnosed.

Does Where You Live Affect Your Risk of Developing IBD?

Unfortunately, where you live may play a role. According to the Mayo Clinic, those who live in urban or industrialized countries have a much higher risk than those who live in more rural areas. This may be in part due to the pollution that is present in urban and industrialized areas, causing cells to not heal as well.

Also, those who live in urban and industrialized areas tend to have a diet that is lower in fiber and higher in protein and fat. Fiber helps promote good digestive health, so diets high in fiber are less apt to become diseased. Another reason they are more apt to become ill is because those those who live in urban and industrialized countries have more access to health care and doctors; therefore, they are more apt to get symptoms checked out.

Do You Believe that What You Eat Causes Certain Illnesses to Appear?

See results

Does Accutane Cause IBDs?

Some people believe that illnesses are caused by the foods we eat or even the medicines we ingest. One medication that has been rumored to cause IBDs is Accutane. According to the Mayo Clinic in a blog published in 2015, there is no association between the two.

Since previously there were some studies that stated that there was a correlation, they discontinued this acne brand, although you can still find it under the names: Amnesteem, Claravis and Sotret. There have also been many other studies that have not shown any correlation; therefore, if you are already at risk, you should proceed with caution. The active medication in Accutane is isotretinoin, which is what you want to look for if you have concerns and want to take acne medication.

Source

Can Stress Cause Inflammatory Bowel Diseases?

Another misconception is that stress causes IBDs. Stress does not cause a disease to appear, but stress can cause a disease to flare-up. This is true no matter if the disease is intestinal or in any other part of the body. Diseases are caused by a gene, which means, stress cannot cause a disease to appear unless it is already present in a person's body. On the other hand, stress can cause a disease to have symptoms appear that may not have presented themselves without the stressor.

Just as physical stressors can cause a flare, so can allergens, which are stresses to the body. IBDs are believed to be irritated by an allergen that gets into the digestive tract. When the allergen is detected the intestinal tract overreacts in those who have an IBD. As the body fights against the allergen, it also fights against itself. This overreaction may be increased by someone who is under a lot of stress.

No one will be able to predict whether their child will have an IBD, nor can they cause a child's illness to be less severe. If you believe your child is showing symptoms of the disease, it is important to have them checked by a doctor to assure they have a healthy digestive system.

Citation

  • "Crohn's Disease." Mayo Clinic. March 08, 2018. Accessed March 21, 2018. https://www.mayoclinic.org/diseases-conditions/crohns-disease/symptoms-causes/syc-20353304.
  • "No Association Between Isotretinoin Exposure and IBD." Mayo Clinic. Accessed March 21, 2018. http://ibdblog.mayoclinic.org/2015/09/13/no-association-between-isotretinoin-exposure-and-ibd/.

Questions & Answers

© 2010 Angela Michelle Schultz

Comments

    0 of 8192 characters used
    Post Comment

    • angela_michelle profile imageAUTHOR

      Angela Michelle Schultz 

      6 years ago from United States

      I'm glad to help.

    • profile image

      reflux 

      6 years ago from USA

      Thanks for this hub. Its really knowledgeable hub.

    • angela_michelle profile imageAUTHOR

      Angela Michelle Schultz 

      8 years ago from United States

      Thanks for the great information! All of that seems to coincide what I read in 2002, but I didn't know if the statistics were still accurate, and must have chose to leave them out! Thanks for adding to my article. I appreciate your comment.

    • profile image

      LorianNina 

      8 years ago

      Thank you for the great article and the great info.

      I am a person who likes numbers, so I just wanted to share the numbers I was able to find on this topic:

      The info I have found indicates that: (according to info at cdc.gov, cited below)

      The worldwide incidence rate of ulcerative colitis seems to vary greatly between 0.5–24.5/100,000 persons, while that of Crohn’s disease seems to vary between 0.1–16/100,000 persons, worldwide.

      And also that: (according to info at genome.gov, cited below)

      About 20 percent (1 in 5) of people who have Crohn's disease have a blood relative with some form of inflammatory bowel disease, usually a brother or a sister, and sometimes a parent and child.

      There appears to be a risk for inheriting Crohn's disease, especially in families of Jewish ancestry.

      Children who have one parent with Crohn's disease have a 7 to 9 percent lifetime risk of developing the condition. They also have a 10 percent chance to develop some form of inflammatory bowel disease. When both parents have inflammatory bowel disease, the risk for their children to develop Crohn's disease is 35 percent.

      I'm sorry that I could not find as much info for UC.

      [ Sources:

      http://www.cdc.gov/ibd/

      http://www.genome.gov/25521854

      ]

    • Pamela99 profile image

      Pamela Oglesby 

      8 years ago from Sunny Florida

      Very good information. Good hub.

    • angela_michelle profile imageAUTHOR

      Angela Michelle Schultz 

      8 years ago from United States

      Having suffered from severe case of ulcerative colitis that has led to 10+ surgeries, BM 20+ times a day, I will say it didn't ruin my life. I think we have to watch our attitude no matter what our bodies do. We can let it ruin our lives, but we can force ourselves to enjoy life despite. It can affect our lives so tremendously, but only us, ourselves, can ruin our lives.

    • GarnetBird profile image

      Gloria Siess 

      8 years ago from Wrightwood, California

      Good informative Hub; these disorders can really flare-up and ruin a person's life if they are not controlled. Good job!

    working

    This website uses cookies

    As a user in the EEA, your approval is needed on a few things. To provide a better website experience, healdove.com uses cookies (and other similar technologies) and may collect, process, and share personal data. Please choose which areas of our service you consent to our doing so.

    For more information on managing or withdrawing consents and how we handle data, visit our Privacy Policy at: https://healdove.com/privacy-policy#gdpr

    Show Details
    Necessary
    HubPages Device IDThis is used to identify particular browsers or devices when the access the service, and is used for security reasons.
    LoginThis is necessary to sign in to the HubPages Service.
    Google RecaptchaThis is used to prevent bots and spam. (Privacy Policy)
    AkismetThis is used to detect comment spam. (Privacy Policy)
    HubPages Google AnalyticsThis is used to provide data on traffic to our website, all personally identifyable data is anonymized. (Privacy Policy)
    HubPages Traffic PixelThis is used to collect data on traffic to articles and other pages on our site. Unless you are signed in to a HubPages account, all personally identifiable information is anonymized.
    Amazon Web ServicesThis is a cloud services platform that we used to host our service. (Privacy Policy)
    CloudflareThis is a cloud CDN service that we use to efficiently deliver files required for our service to operate such as javascript, cascading style sheets, images, and videos. (Privacy Policy)
    Google Hosted LibrariesJavascript software libraries such as jQuery are loaded at endpoints on the googleapis.com or gstatic.com domains, for performance and efficiency reasons. (Privacy Policy)
    Features
    Google Custom SearchThis is feature allows you to search the site. (Privacy Policy)
    Google MapsSome articles have Google Maps embedded in them. (Privacy Policy)
    Google ChartsThis is used to display charts and graphs on articles and the author center. (Privacy Policy)
    Google AdSense Host APIThis service allows you to sign up for or associate a Google AdSense account with HubPages, so that you can earn money from ads on your articles. No data is shared unless you engage with this feature. (Privacy Policy)
    Google YouTubeSome articles have YouTube videos embedded in them. (Privacy Policy)
    VimeoSome articles have Vimeo videos embedded in them. (Privacy Policy)
    PaypalThis is used for a registered author who enrolls in the HubPages Earnings program and requests to be paid via PayPal. No data is shared with Paypal unless you engage with this feature. (Privacy Policy)
    Facebook LoginYou can use this to streamline signing up for, or signing in to your Hubpages account. No data is shared with Facebook unless you engage with this feature. (Privacy Policy)
    MavenThis supports the Maven widget and search functionality. (Privacy Policy)
    Marketing
    Google AdSenseThis is an ad network. (Privacy Policy)
    Google DoubleClickGoogle provides ad serving technology and runs an ad network. (Privacy Policy)
    Index ExchangeThis is an ad network. (Privacy Policy)
    SovrnThis is an ad network. (Privacy Policy)
    Facebook AdsThis is an ad network. (Privacy Policy)
    Amazon Unified Ad MarketplaceThis is an ad network. (Privacy Policy)
    AppNexusThis is an ad network. (Privacy Policy)
    OpenxThis is an ad network. (Privacy Policy)
    Rubicon ProjectThis is an ad network. (Privacy Policy)
    TripleLiftThis is an ad network. (Privacy Policy)
    Say MediaWe partner with Say Media to deliver ad campaigns on our sites. (Privacy Policy)
    Remarketing PixelsWe may use remarketing pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to advertise the HubPages Service to people that have visited our sites.
    Conversion Tracking PixelsWe may use conversion tracking pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to identify when an advertisement has successfully resulted in the desired action, such as signing up for the HubPages Service or publishing an article on the HubPages Service.
    Statistics
    Author Google AnalyticsThis is used to provide traffic data and reports to the authors of articles on the HubPages Service. (Privacy Policy)
    ComscoreComScore is a media measurement and analytics company providing marketing data and analytics to enterprises, media and advertising agencies, and publishers. Non-consent will result in ComScore only processing obfuscated personal data. (Privacy Policy)
    Amazon Tracking PixelSome articles display amazon products as part of the Amazon Affiliate program, this pixel provides traffic statistics for those products (Privacy Policy)