What Are the Chances My Children Will Inherit Ulcerative Colitis or Crohn's Disease?

Updated on March 21, 2018
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At 17, Angela was diagnosed with ulcerative colitis. At 20, her colon was removed. She has a passion to share her knowledge of the disease.

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Is Ulcerative Colitis and Crohn's Hereditary?

Ulcerative colitis and Crohn's, both of which are inflammatory bowel diseases (IBD), can be hereditary diseases. A child who has a sibling or parent with an IBD has a twenty percent chance of being diagnosed with one of these in their lifetime. At this time, it is impossible to genetically test who is going to get the disease or who will not; they have not yet identified a gene that causes IBDs.

Crohn's and ulcerative colitis are unique in that they are so interrelated that if a parent or sibling has one, another relative is just as likely to have the other one. This means that if ulcerative colitis runs in your family, a person is just as likely to have Crohn's as ulcerative colitis.

Just as with any other disease, the odds increase if both parents are diagnosed. The likelihood drastically increases up to an eighty percent chance of having one or the other if both parents have an IBD. The severity of the illness, on the other hand, is not hereditary. One person may have a mild case that is easily managed through diet and medication, while another person cannot get theirs under control no matter what they try and eventually will need surgery in order to place it in remission.

If you were diagnosed with an IBD, what age were you when you were diagnosed?

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At What Age Do People Tend to Get Diagnosed?

Unfortunately, just as you cannot predict how severe a child's disease will be, you may not be able to tell whether they have it until they are adults.

Crohn's is common to appear in all age groups equally, although most people are diagnosed before thirty-years old. Ulcerative colitis, on the other hand, has a high tendency to show up at two different times in one's life. Most people have their first symptoms in their teens or twenties. The likelihood increases again when the person is fifty to sixty-five. This is believed to be due to the shift in hormones that occurs at both of these ages. Yet, any person of any age can be diagnosed and/or show symptoms of ulcerative colitis.

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What Races Are Most Likely to Have an IBD?

Since the disease is genetic, some races are more apt to be diagnosed with an inflammatory bowel disease than others. Asian or African descendants are unlikely to have either of these diseases, while Caucasians have the highest tendency. Also those who have Jewish ancestry have a higher likelihood than non-Jewish ancestry to have an IBD. Still, any person of any race may be diagnosed.

Does Where You Live Affect Your Risk of Developing IBD?

Unfortunately, where you live may play a role. According to the Mayo Clinic, those who live in urban or industrialized countries have a much higher risk than those who live in more rural areas. This may be in part due to the pollution that is present in urban and industrialized areas, causing cells to not heal as well.

Also, those who live in urban and industrialized areas tend to have a diet that is lower in fiber and higher in protein and fat. Fiber helps promote good digestive health, so diets high in fiber are less apt to become diseased. Another reason they are more apt to become ill is because those those who live in urban and industrialized countries have more access to health care and doctors; therefore, they are more apt to get symptoms checked out.

Do You Believe that What You Eat Causes Certain Illnesses to Appear?

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Does Accutane Cause IBDs?

Some people believe that illnesses are caused by the foods we eat or even the medicines we ingest. One medication that has been rumored to cause IBDs is Accutane. According to the Mayo Clinic in a blog published in 2015, there is no association between the two.

Since previously there were some studies that stated that there was a correlation, they discontinued this acne brand, although you can still find it under the names: Amnesteem, Claravis and Sotret. There have also been many other studies that have not shown any correlation; therefore, if you are already at risk, you should proceed with caution. The active medication in Accutane is isotretinoin, which is what you want to look for if you have concerns and want to take acne medication.

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Can Stress Cause Inflammatory Bowel Diseases?

Another misconception is that stress causes IBDs. Stress does not cause a disease to appear, but stress can cause a disease to flare-up. This is true no matter if the disease is intestinal or in any other part of the body. Diseases are caused by a gene, which means, stress cannot cause a disease to appear unless it is already present in a person's body. On the other hand, stress can cause a disease to have symptoms appear that may not have presented themselves without the stressor.

Just as physical stressors can cause a flare, so can allergens, which are stresses to the body. IBDs are believed to be irritated by an allergen that gets into the digestive tract. When the allergen is detected the intestinal tract overreacts in those who have an IBD. As the body fights against the allergen, it also fights against itself. This overreaction may be increased by someone who is under a lot of stress.

No one will be able to predict whether their child will have an IBD, nor can they cause a child's illness to be less severe. If you believe your child is showing symptoms of the disease, it is important to have them checked by a doctor to assure they have a healthy digestive system.

Citation

  • "Crohn's Disease." Mayo Clinic. March 08, 2018. Accessed March 21, 2018. https://www.mayoclinic.org/diseases-conditions/crohns-disease/symptoms-causes/syc-20353304.
  • "No Association Between Isotretinoin Exposure and IBD." Mayo Clinic. Accessed March 21, 2018. http://ibdblog.mayoclinic.org/2015/09/13/no-association-between-isotretinoin-exposure-and-ibd/.

Questions & Answers

    © 2010 Angela Michelle Schultz

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      • angela_michelle profile image
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        Angela Michelle Schultz 6 years ago from United States

        I'm glad to help.

      • profile image

        reflux 6 years ago from USA

        Thanks for this hub. Its really knowledgeable hub.

      • angela_michelle profile image
        Author

        Angela Michelle Schultz 7 years ago from United States

        Thanks for the great information! All of that seems to coincide what I read in 2002, but I didn't know if the statistics were still accurate, and must have chose to leave them out! Thanks for adding to my article. I appreciate your comment.

      • profile image

        LorianNina 7 years ago

        Thank you for the great article and the great info.

        I am a person who likes numbers, so I just wanted to share the numbers I was able to find on this topic:

        The info I have found indicates that: (according to info at cdc.gov, cited below)

        The worldwide incidence rate of ulcerative colitis seems to vary greatly between 0.5–24.5/100,000 persons, while that of Crohn’s disease seems to vary between 0.1–16/100,000 persons, worldwide.

        And also that: (according to info at genome.gov, cited below)

        About 20 percent (1 in 5) of people who have Crohn's disease have a blood relative with some form of inflammatory bowel disease, usually a brother or a sister, and sometimes a parent and child.

        There appears to be a risk for inheriting Crohn's disease, especially in families of Jewish ancestry.

        Children who have one parent with Crohn's disease have a 7 to 9 percent lifetime risk of developing the condition. They also have a 10 percent chance to develop some form of inflammatory bowel disease. When both parents have inflammatory bowel disease, the risk for their children to develop Crohn's disease is 35 percent.

        I'm sorry that I could not find as much info for UC.

        [ Sources:

        http://www.cdc.gov/ibd/

        http://www.genome.gov/25521854

        ]

      • Pamela99 profile image

        Pamela Oglesby 8 years ago from United States

        Very good information. Good hub.

      • angela_michelle profile image
        Author

        Angela Michelle Schultz 8 years ago from United States

        Having suffered from severe case of ulcerative colitis that has led to 10+ surgeries, BM 20+ times a day, I will say it didn't ruin my life. I think we have to watch our attitude no matter what our bodies do. We can let it ruin our lives, but we can force ourselves to enjoy life despite. It can affect our lives so tremendously, but only us, ourselves, can ruin our lives.

      • GarnetBird profile image

        Gloria Siess 8 years ago from Wrightwood, California

        Good informative Hub; these disorders can really flare-up and ruin a person's life if they are not controlled. Good job!

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