How to Get Rid of a Fever Blister Fast

Huge fever blister on  my lip!  This is what happens when it's not treated in the beginning of the infection.
Huge fever blister on my lip! This is what happens when it's not treated in the beginning of the infection. | Source

If you get fever blisters like I do, you know only too well how hideous they are! You begin to feel the tingling and know that you are in for days of pain and an embarrassing honker hanging out for all the world to see. Granted, there's never a good time for a cold sore... but it never seems to fail an outbreak seems to coincide with something important: a first date, an interview, a vacation, a family reunion or a class reunion. I've been getting these awful creature for 40 years now... Over the past four decades I've tried anything and everything to stop them, keep them at bay and obliterate them as quickly as possible. Some fever blister remedies have helped a little, some a lot and some have been a waste of time and money.

If you are as fed up as I became, read on. Through trial and error I've come across an inexpensive, nonprescription medication to get rid of a fever blister very quickly...

A Primer on Fever Blisters, Also Knows as Cold Sores

There seems to be a stigma surrounding fever blisters, most likely because they are caused by the Herpes family of viruses. Herpes Simplex, Type 1 (HSV 1) is the kind that causes oral Herpes. It's a different strain from Herpes Simplex 2 (HSV 2), the kind that causes genital Herpes. Just because I have HSV 1 it does NOT mean I have HSV 2! I don't, in fact... nor do many sufferers of the oral type. So quit staring, quit being afraid and quit judging. Many of us contracted this virus in childhood, through family member with HSV 1. We aren't promiscuous, sexual deviants... we have a lifelong virus that happens to reside in our central nervous systems just waiting for our immune systems to break down.

The majority of people with HSV 2 got it from others who also have HSV 2. Oral Herpes CAN cause an infection of genital Herpes, however.

The nasty virus that causes fever blisters lies dormant in our central nervous system, more specifically the brain. During an immune breakdown, it travels down your cranial nerves and causes the blisters you see on, around and sometimes even IN your mouth. These blisters are actually your immune system's response to fighting off the virus. And, it's clearly not an attractive response... much like the unattractive phlegm we produce when suffering from the common cold.

Bactine is a life-saver for fever blisters!
Bactine is a life-saver for fever blisters!

How to Get Rid of a Fever Blister With Over-The-Counter Medicine... AND FAST!

My mother, grandmother and I have all suffered from these oral outbreaks. I started getting them when I was 5. My mother would douse them in medicated Blistex. In my grandmother's adult years, she began getting them too. She swore that putting rubbing alcohol on them, at the very first sign of the tickly twinge, would help reduce their severity. This was quite the opposite of the treatment I'd been using for many years. I was actually keeping mine moisturized! I did find the rubbing alcohol helped somewhat, but I was determined to improve upon this home remedy.

I'm pretty sure I can't name all the different products, concoctions and downright crazy remedies I've tried over the years. I would have done anything in high school to reduce their frequency and shrink their enormity! Let me share with you what actually works... or works in my case. We are all different, so different treatments might work better for some than others.

First, let me say that my grandmother was right: you always need to catch the little buggers when they first begin in what's called the prodromal stage. The first sign of impending doom is often that characteristic itchy tingle. THIS is the time to act... and act fast. Always carry your preferred method of treatment with you or keep it in your car.

Best Methods for Treatment


How does it work on the Herpes Virus? The active ingredient in Bactine is Benzalkonium Chloride 0.13%, the exact same ingredient used in the "miracle product" Viroxyn. Bactine is an inexpensive, over-the-counter antiseptic wash used to treat cuts and scrapes. Don't bother buying Viroxyn, unless you want to spend way more for the exact same product. The Benzalkonium Chloride in Bactine basically destroys what's called the "lipid coat" on the virus so that the virus is unable to attach to the skin's cells. The herpes virus is enclosed by an envelope of fat that helps the virus enter and invade the cells.

How To Use Bactine

As mentioned previously, the best way to fight this virus is as quickly as possible. At the first sign of the winge, tickle, tingle or pain apply the Bactine with a cotton ball or a Q-Tip. I use a Q=Tip to avoid spreading the virus as much as possible. You don't want to just glob it on and call it done, though. Apply a decent amount and lightly rub it onto the affected area. Bactine has lidocaine in it which will numb the skin. Once the skin is numb, begin to rub harder and more vigorously but avoid breaking the skin!

I'm telling you, I've had REMARKABLE results with this treatment! They either don't develop at all or are extremely mild.

Zinc Oxide

It seems my treatments have us taking a walk down memory lane, huh? First, I recommend Bactine, the stuff your mother used to chase after you with after you fell off your bike. Now, zinc oxide- the active ingredient in many diaper rash formulas??? I guess there's something to be said for the good old days, huh?

I'm not just making this stuff up, though. There's actually some scientific evidence the zinc oxide treatment works. A combination zinc oxide/glycine cream was given to patients in the first 24 hours of herpes simplex 1 symptoms. They applied the cream every 2 hours until either the cold sore had healed or until the span of three weeks had passed. A placebo was given to the control group. The results showed the group applying the zinc oxide/glycine cream had faster healing times than those using the placebo. The ointment also reduced pain, blistering, itching and tingling. I've found these results to hold true when I've used it myself.

How to Use Zinc Oxide

The bummer is the frequency of application. You need to be putting on the cream every two hours without fail. I recommend using a clean Q-Tip for application. Never use the same Q-Tip to treat multiple areas or you risk spreading the virus.

Notes About Abreva

Funny thing this Abreva stuff is... When it first came out I was thrilled! I purchased it from my drugstore and waited (almost excitedly) for my outbreak. It came (of course) and I was ready with my new panacea, Abreva. Well, let me say... it worked wonders! In fact, it worked wonders for a few months. It substantially reduced the blistering and the healing time. I thought I'd found my remedy.

Here's where it gets funny... okay it's not really very funny at all. It just STOPPED working for me! What the heck? I don't have a good explanation as to why it no longer works for me, but I've done some reading on the subject and I'm not alone. That's not to say it won't work or continue to work for you, however!

L-Lysine is well worth taking for fever blister prevention.
L-Lysine is well worth taking for fever blister prevention. | Source

An Ounce of Prevention...

  • If you have yet to try L-Lysine, do so! It's dramatically reduced the number of cold sores I get. Lysine is one of the nine essential amino acids and seemingly hinders the reproduction of the Herpes Simplex virus. 3g per day is recommended for the prevention of fever blisters and 3 to 9 g per day when you actually have an outbreak.
  • Make sure (absolutely sure) to wear sunscreen... especially on your lips. Sun exposure is strongly correlated with an outbreak.
  • Keep your treatment with you at all times! Keep it in your purse, ladies. Get a man purse (murse) or something like it, gentlemen. Or, as I previously mentioned- keep it in your car. You must catch it in the prodromal stage!

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Comments 3 comments

Bobbie 2 years ago

Thanks! I'm suffering horribly right now. .my poor face is covered in fever blisters! I'm going to try the tips you gave before my next outbreak. .I am certain there will be one! Using Abreva..hopefully it will work. ..I truly HATE cold sores :(

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wordscribe43 3 years ago from Pacific Northwest, USA Author

Cloverleaf- never heard of using lemon balm, thanks for that. Yes, I do know oral can transfer as genital, I make mention of that. Scary stuff these fever blisters. Off to research about the lemon balm!

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cloverleaffarm 3 years ago from The Hamlet of Effingham

Great hub. Did you know that oral herpes can transfer as genital herpes? While HSV1 is not necessarily an STD, it becomes one when transferred. 80% of Americans have herpes cold sores. Many don't know it, as it still lays dormant. 35% have HSV2.

For people looking for a more natural approach, lemon balm works in just a couple of days, and with continued use, it can stop them from breaking out.

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